Lauren Goins, PhD
Lauren Goins, PhD
Jewel Banik, PhD
Jewel Banik, PhD
Bayan Kharrat, PhD
Bayan Kharrat, PhD
Zoya A. Gauhar
Zoya A. Gauhar
Christina Rouhotas
Christina Rouhotas
Celeste Sanchez
Celeste Sanchez
Julie Sanchez
Julie Sanchez
Benjamin Bolival
Benjamin Bolival
Chenelle Hill
Chenelle Hill
Jessica Kissi
Jessica Kissi
Ilana Mendez
Ilana Mendez
Ashwin Hariharan
Ashwin Hariharan
Nandini Rahul Manepalli
Nandini Rahul Manepalli
Headshot of Dr. Lauren Goins, Principal Investigator of the Goins Lab at Stanford Medicine

Lauren Goins, PhD

Principal Investigator

I am a developmental biologist interested in how cells make decisions in complex, living environments. My path to studying blood stem cells began with a fascination for the cytoskeleton and live imaging, and evolved through training in Drosophila genetics, where I learned the power of observing cell behavior directly in vivo. These experiences continue to shape how I think about stem cell regulation, fate choice, and the importance of spatial and temporal context in biology. 

My research centers on how hematopoietic stem and progenitor cells decide when to self-renew, differentiate, or respond to stress. Broadly, I am interested in how cells integrate extracellular cues from their environment with intrinsic regulatory programs, including cell-cycle control, polarity, and cytoskeletal organization. More specifically, my lab investigates how spatially and temporally regulated signaling pathways—such as Wnt/β-catenin, EGFR, JNK, and redox signaling—intersect with cell-cycle progression to control fate transitions, with a particular focus on asymmetric cell division in vivo. We use Drosophila as a discovery platform to identify conserved mechanisms that inform mammalian blood biology and disease.

Beyond the bench, I am deeply motivated by mentorship, teaching, and building inclusive scientific communities. I care strongly about training scientists at all stages, demystifying the research process, and creating lab environments where curiosity, rigor, and collaboration thrive. I am also inspired by connecting basic discovery to broader human impact—whether through public engagement, interdisciplinary collaboration, or supporting the next generation of scientists in finding their voice and place in science.

Selected Publications

A novel role for Hsc70-4 in blood cell differentiation in Drosophila

Kharrat B., Gábor E., Vilmos P., Goins LM., Honti V. (2025)

Wnt signaling couples G2 phase control with differentiation during hematopoiesis in Drosophila

Goins LM., Girard JR., Mondal BC., Buran S., Su CC., Tang R., Biswas T., Kissi JA., Banerjee U. (2024)

A conserved mechanism for JNK-mediated loss of Notch function in advanced prostate cancer

Wang CW., Clémot M., Hashimoto T., Diaz JA., Goins LM., Goldstein AS., Nagaraj R., Banerjee U. (2023)

Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis

Girard JR., Goins LM., Vuu DM., Sharpley MS., Spratford CM., Mantri SR., Banerjee U. (2021)