The Path We Walk
Cell fate decisions lay at the heart of the Goins lab. Young, immature blood cells have the potential to become a diverse set of mature cell types during blood development. We work to uncover the molecular and cellular mechanisms driving these fate decisions from beginning to end.
The Questions We Ask
Understanding how cells make fate decisions during hematopoiesis is a central focus of the lab. To explore the mechanisms that govern these complex processes, we ask the following questions:
- How do stem cells and progenitors navigate distinct developmental paths to generate blood cell diversity?
- How do extracellular signals integrate with intracellular programs to coordinate cell cycle progression and fate decisions in vivo?
- When and how do hematopoietic progenitors divide asymmetrically to balance self-renewal and differentiation?
- How are homeostatic stem cell behaviors and fate decisions rewired in response to stress, injury, and disease?
Join Us
In the Goins Lab, we value collaborative, team-based science driven by open discussion and shared curiosity. If you’re interested in joining our team, please contact Dr. Lauren Goins.
Contact Us